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first demonstrated in the LPS-induced ALI model that pretreatment of salidroside inhibited the inflammatory cytokines (TNF-, IL-6, and IL-1), relieved pulmonary edema, and reduced the number of inflammatory cells in the BALF (Guan et al., 2012)

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Consistently, the MSI-H group had the lowest SAAM score (Figure S6F)

However, this pathway can become detrimental when overactivated in GBM, promoting tumorigenesis and contributing to resistance to therapeutic interventions [143]