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Studies have shown that curcumin (an extract of turmeric) can improve symptoms of knee arthritis as well as a non-steroidal anti-inflammatory drug

Instead, the sponsor notifies the TGA about the trial and provides details of the investigational product

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This systematic chronic low-grade inflammation is therefore likely to contribute to pain symptoms experienced by some women with PCOS, particularly pelvic pain, via mechanisms involving peripheral and central sensitization (Lu et al., 2022)

However, it's important to contextualize this assessment within the limitations of the available evidence: most safety data comes from relatively small studies, often of short-to-moderate duration, conducted primarily in the Soviet Union, Russia, and Eastern Europe where methodological standards and reporting practices have sometimes differed from Western pharmaceutical trial requirements