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Similarly, TFEB-mediated autophagy played a crucial role in the protective effects of UA in BV2 cells by upregulating the expressions of Beclin-1, LAMP1, and the LC3II/I ratio, while the knockdown of TFEB by siRNA markedly decreased autophagy activity in A + UA-treated BV2 cells

Distinct Fibroblast Growth Factor (FGF)/FGF Receptor Signaling Pairs Initiate Diverse Cellular Responses in the Oligodendrocyte Lineage

Wolvers D

1994;24:S16S24

The assembled DNA cassette was digested with SfiI and ligated upstream of C H 1-p3 into the SfiI-digested phagemid using T4 DNA ligase, yielding phagemids encoding Fabs linked to the N-terminus of a fragment of protein III (pIII: amino acids 230406) of filamentous phage M13 42

Pregnancy: Teratogenic Effects: In a teratology study of acetylcysteine solution in the rabbit, oral doses of 500 mg/kg/day (2.6 times the human mucolytic dose) were administered to pregnant does by intubation on days 6 through 16 of gestation