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Recent studies suggest that PG may lead to mitochondrial dysfunction and inhibit cellular respiration, resulting in ATP depletion (Dolatabadi et al

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Her practitioner advised a temporary reduction in dosage, and also changed the type of antimicrobials she was taking as she had an issue with Histamine

Perhaps this has to do with the specific discrete mutational event causing their development

Crit Rev Toxicol 51:634652

In this context, nanotechnol.-based approaches such as nanoparticle drug delivery emerge as the most promising option