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Front Cardiovasc Med 8:721814

It has been studied in preclinical models for its effects on NNMT-mediated metabolic pathways, adipocyte differentiation, and NAD+ salvage pathway modulation

This is a mechanistic limitation, not a flaw unique to AOD-9604

Low levels of vitamin B12 affect the reproductive organs

These effects are essential for maintaining energy efficiency under metabolic stress, supporting research into fatigue resistance and cellular longevity

A doctor may recommend vitamin B12 shots for people at risk of a deficiency or its complications, particularly if they are unable to take oral supplements