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Consequently, this accumulation feeds a vicious cycle that exacerbates oxidative stress, accelerates tau hyperphosphorylation, and ultimately drives synaptic failure and neuronal apoptosis

Rodriguez-Iturbe B, Vaziri ND, Herrera-Acosta J, Johnson RJ

[DOI] [PMC free article] [PubMed] [Google Scholar] [28].Huhti E, Poukkula A, Uksila E

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The sequences of the negative control were: 5-UUC UCC GAA CGU GUC ACG UTT-3 and 5-ACG UGA CAC GUU CGG AGA ATT-3

You should also see a clinician if you have anemia symptoms, a history of gastric surgery, suspected pernicious anemia, or if lab testing hasnt confirmed a B12 deficiency.