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4.2.2 Metabolite supplementation and receptor modulation Direct administration of key metabolites offers a complementary approach to restore metabolic balance

Calcium oxalate, the predominant form of oxalate found in soils, plants, and in the human body forms insoluble solids that can linger as toxic minute crystal deposits in tissuesincluding the heart, thyroid, and bone marrow

The upregulation of NADPH oxidases (NOX enzymes) in tumour cells and tumor-associated macrophages (TAMs) also contributes to oxidative stress [43]

doi: 10.1016/j.tifs.2018.05.012 43

While BM, AD, and UC-derived MSCs have all been demonstrated to express synaptophysin as evidence of the formation of a synapse 102 , AD-derived MSCs were exhibited to express the highest level of SAP-90 as compared to BM- and UC-derived MSCs, which indicates that AD-derived MSCs may be more likely to form synaptic structures 103

These reactions include mild redness, swelling, or tenderness at the injection location