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Inhibitory effect of silibinin on hepatitis B virus entry
They both require pyridoxal-5-phosphate, the active form of vitamin B6, as a cofactor for their enzymatic activity [26, 27, 28]

For example, Nrf2 knockout in the aging mice reduced iron ions deposition in the brain, lowered the level of oxidative damage in the striatum, and also alleviated the age-related motor dysfunction [80]

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