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In HNSCC, in vitro knockdown of SMAD 4 induced cetuximab resistance by activating TGF- and c-MET pathways [99]

doi: 10.1007/s00421-009-1216-1

Wu, Y., Tang, L., & Chen, B

2025;12:e269-e281

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We found that the degree of spindle abnormalities was low before 12h, but increased significantly at 24h, and the spindle defects could be partially rescued by Epitalon (Figure 3A, 3B), suggesting that Epitalon can reduce oocyte spindle defects
