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[2] However, elevated MMA is not conclusive, as it is seen in people with B 12 deficiency, but also in elderly people who have renal insufficiency, [28] and elevated homocysteine is not conclusive, as it is also seen in people with folate deficiency

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Response timelines vary significantly depending on the severity of illness, how long symptoms have persisted, and which symptom cluster is being targeted
doi: 10.1073/pnas.1308905110
