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Chronic hyperlgycemia can lead to vacuolization and atrophy or degeneration of myelinated nerve fibers [127]
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Burnichon, N., et al

This stacking approach lacks formal study but has theoretical basis
The inhibition of the PD-1 pathway results in enhanced survival outcomes in animal models of bacterial and fungal sepsis that closely resemble the clinical context (Brahmamdam et al., 2010
