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Vial Puncture Frequency and Contamination Risk Over Time Every needle puncture introduces three degradation accelerators: atmospheric oxygen, trace particulate matter, and potential microbial contamination

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We investigate a particular aspect of the sudden onset of encephalopathy with paracetamol overdose (for review see 1-3) so far not reported: may paracetamol rapidly induce hepatic encephalopathy with generalized convulsions in rats and if so, the possible therapy effect in early and advanced stage

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doi: 10.1113/JP287342

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