b12 injection im dose Cyanocobalamin (b12) 2,000 mcg/mL 30mL Conquer Pharma Intrav – My Store Cyanocobalamin Injection – 1000 mcg/mL

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Some medical conditions may also increase the risk of deficiency

Cobalamin separates from the protein during digestion, and a substance called intrinsic factor binds to cobalamin for the body to absorb it into the blood

330 Computed tomography venography (CTV ) and magnetic resonance venography (MRV) appear to have similar accuracy to CUS for diagnosing DVT, but are not widely used because of their invasive nature (ie, since they involve intravenous injections of contrast solutions)

Vitamin B12 There is four types of parenteral Vitamin B12 available: Cyanocobalamin 100 mcg/ml and 1000 mcg/ml best used as IM to prevent rapid loss via kidneys Hydroxycobalamin IM (compounded 1000 mcg/ml or more) known as long acting B12 (binds better to plasma proteins than cyanocobalamin) Methylcobalamin IV (compounded 1000 mcg or more up to 5000 mcg/ml) Adenosylcobalamin IV Common dose is 1000 mcg IM or IV Vitamin B12 as hydroxycobalamin is synthesized exclusively by microorganisms and is found in the liver of animals bound to protein as methylcobalamin = metabolically active form of Vitamin B12 Hydroxycobalamin is a chelator of cyanide and is used in cyanide poisoning Hydroxocobalamin is most generally used for vitamin B12 replacement therapy and is considered the drug of choice for vitamin B12 deficiency by the Martindale Extra Pharmacopoeia (Sweetman, 2002) and the World Health Organization (WHO) Model List of Essential Drugs