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In this context, microglia and neurons developed an iron-accumulating phenotype [39]

doi: 10.1016/j.cgh.2006.03.020 164 MorrowDMFitzsimmonsPEChopraMMcGlynnH

[PubMed 14632591] 2487

Among ascorbic acid derivatives, fatty acid esters of ascorbic acid viz., ascorbyl palmitate and ascorbyl stearate have attracted considerable interest as anticancer compounds in view of their lipophilic nature as they can easily cross cell membranes and blood brain barrier [76]

Mendez, 2017), culminating in the development of dementia, including increased risk for cerebral atrophy, CTE and even Parkinsons disease (PD)

Funding This work was supported by the National Key R&D Program of China Scientific and Technological Innovation of Blue Granary (2018YFD0901504), the National Natural Science Foundation of China (31672630), the earmarked fund for CARS-50, Shandong Province Key Research and Development Program (2022LZGC004, 2021LZGC004), the Central Public-interest Scientific Institution Basal Research Fund (2020TD27)