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Darkness of the skin depends on the concentration of skin pigment Melanin synthesized in the basal level of epidermis

Glutathione stops the catalytic activity of Tyrosinase, an enzyme directly responsible for melanin production

Overexpression of glutathione reductase but not glutathione synthetase leads to increases in antioxidant capacity and resistance to photoinhibition in poplar trees

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doi: 10.21037/tau.2017.05.40 65 AitkenRJ

Genetic variations in the catalase gene and in its promoter region also play a role in the pathogenesis of various diseases which is depicted in Figure 6
