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Profile of Cognitive Impairment in Parkinson's Disease
ROS marked by 4-HNE was significantly increased in the control aged group as compared to young rats, but the increase in ROS in the AST group was significantly lowered

Funct Integr Genomics 23 , 212 (2023)

Oxysophoridine protects against cerebral ischemia/reperfusion injury via inhibition of TLR4/p38MAPKmediated ferroptosis

By downregulating NF-B and increasing Nrf2 activation, the entkauranoid diterpenoid glaucocalyxin-B, which is produced from Rabdosia japonica, was demonstrated to decrease oxidative stress and inflammation in a PD rat model caused by LPS [119]

Further placebo-controlled clinical trials are needed to confirm glutathiones safety and effectiveness, with melanin index measurements serving as an objective way to track skin pigmentation changes
