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Hepa-1c1c7 cells were transfected with CPT1/2 and carnitine acylcarnitine translocase (CACT) siRNA and then challenged with 800 M PA with 150 g/mL Godex

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PCA were calculated on log normalized counts using plotPCA from DESeq2 package

Aging often worsens this resistance through chronic high insulin levels

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Sources: Jzwiak, Bauer, Kamysz, Kleczkowska Multifunctionality and Possible Medical Application of the BPC 157 Peptide Literature and Patent Review. Pharmaceuticals, MDPI, January 2025