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Early history: studies linking thiol metabolism to oxidative cell death Reduced glutathione (-L-glutamyl-L-cysteinylglycine, GSH) is an essential intracellular antioxidant synthesized from glutamate, cysteine and glycine in two steps by the ATP-dependent cytosolic enzymes glutamate-cysteine ligase (GCL) and glutathione synthetase (GSS) (Figure 1)

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[DOI] [PubMed] [Google Scholar] 190.Ahmad W., Ijaz B., Shabbiri K., Ahmed F., Rehman S

mississippiensis , using polymerase chain reaction to test the primers' specificity with isolated DNA from A

Cancer 5 , 263274 (2005)

2A, the regional MIND values of the two groups exhibited a roughly normal distribution across all 308 regions