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Hyaluronic acid not only protects mtDNA damage from the initial damage caused by free radicals, but it also maintains cell viability and prevents apoptosis via the anti-CD44 antibody

In the Apc Min mice, a model of colorectal carcinogenesis, resveratrol treatment (0.00007%) decrease adenoma number per mouse in a high-fat diet but not in a standard diet [17]

A scheme integrating all MTX-modulated metabolites into a single metabolic panel can be found in Supplementary Figure 4

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These include redness, swelling, tenderness, itching, bruising, and occasionally a small lump or bump under the skin that may persist for several days