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The importance of being cognizant in recognizing these syndromes in a timely manner has been repeatedly emphasized as we consider GAD-positive patients to have a potentially treatable autoimmune disorder with early immunotherapy initiation

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This results in very low absorption rates

Importantly, these phenotypes contrast with the non-inducible liver-specific Gclc KO mouse strain ( Gclc f/f Albumin-Cre), which develops liver failure and dies shortly after birth 30