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Their effects include antioxidant, anti-inflammatory, anti-proliferative, antimicrobial, and cholesterol-lowering properties [71,72,73]

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This may be not only because nicotine is a nicotinic receptor agonist and therefore an opponent of these poisonous metabolites, but nicotine is a strong acetylcholine (ACh) agonist as well 62

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doi: 10.1016/j.tcb.2006.02.006
