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[PubMed] 6.Myers RH

DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-beta deposition in alzheimer's disease

Warburg effect and redox balance

Mutant -synuclein permeabilizes these vesicles causing leakage of the dopamine into the cytoplasm where it autooxidizes producing hydrogen peroxide, superoxide molecules, and toxic dopamine-quinone species creating oxidative stress conditions [122]

What It Is Class: Endogenous tripeptide antioxidant (thiol-based redox buffer) Core roles: Maintains cellular redox homeostasis

In CRC, treatment with catalpol reduced autophagy, triggered apoptosis, decreased cell viability, and regulated SIRT1 expression by increasing miR-34a levels both in-vivo and in-vitro