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Recent studies highlight the effectiveness of NAC in mitigating ROS, fostering pro-repairative microenvironment and enhancing the osteogenic potential and immune regulatory function of cells, which offers a promising role in the treatment of bone injuries and bone tissue engineering (Bdil et al., 2022)

261 Several PMO-based NADs have been approved for treating DMD, including eteplirsen (Exondys 51), 262 golodirsen (Vyondys 53 ), 80 viltolarsen (Viltepso ), 263 and casimersen (Amondys )

[DOI] [PMC free article] [PubMed] [Google Scholar] 207.Ooi S.L., Green R., Pak S.C

On days 14 and 21 following experimental ischemic stroke, TWS119 treatment promoted microglial polarization by activating Wnt/-catenin signaling, which ultimately improved the local inflammatory microenvironment during the chronic phase of ischemic stroke