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Description
CHAC1s primary function involves the degradation of GSH, a crucial antioxidant
Synthesis of cyclosporine
In this microenvironment, CC cells employ a variety of mechanisms to evade recognition and elimination by cytotoxic T lymphocytes and natural killer (NK) cells 4
This includes expansion of tumor-promoting immunoregulatory cell populations such as MDSCs, 24, 108 epigenetic and metabolic changes resulting in immune cell tolerance, 109 induction of negative regulators of pro-inflammatory signaling pathways, 110 and development of T-cell exhaustion
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R., Aranda, E., and Rodrguez-Ariza, A
