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Improvement of functional recovery by chronic metformin treatment is associated with enhanced alternative activation of microglia/macrophages and increased angiogenesis and neurogenesis following experimental stroke
However, standard oral supplements face a significant hurdle: the digestive system
Br J Pharmacol 171(16):39083917 Kuder KJ et al
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Hetz C, Axten JM, Patterson JB (2019) Pharmacological targeting of the unfolded protein response for disease intervention
