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In rabbits and cynomolgus monkeys administered semaglutide during organogenesis, early pregnancy losses and structural abnormalities were observed at below the MRHD (rabbit) and 5-fold or greater the MRHD (monkey)

Degradation of II-spectrin protein by calpain-2 and caspase-3 under neurotoxic and traumatic brain injury conditions

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[66] found that the mammalian DNMTs ( Dnmt3a and Dnmt3b ) can also act as Ca 2+ ion- and redox state-dependent active DNA demethylases

Those interactions are important for tumor growth, because activation and/or inactivation of these proteins may mediate the antiapoptotic effect of MTs

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