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In pathological conditions, endogenous Exos can worsen disease progression by inducing ferroptosis in target cells [100]
doi: 10.3390/ijms241310550 92 TangLZhangCLuLTianHLiuKLuoDet al

Epigenetic reprogramming in mammalian development

Gurtner, G

62,99,100 Together, these reports provide strong evidence that after an APAP overdose, in vivo and in isolated hepatocytes in culture, ferrous iron can be released from lysosomes and then taken up into mitochondria via the MCFU, where it contributes to MPTP opening and cell death (Fig
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