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Currently, temozolomide (TMZ) is the first-line drug for GBM treatment of which efficacy is unfortunately hindered by short circulation time and drug resistance associated to hypoxia and redox tumor microenvironment

Collagen supplements are generally safe and have a low risk of interactions with medications

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Its dual mechanism as a GLP-1 receptor agonist provides powerful effects on both glycemic control and body weight regulation, with efficacy that exceeds previous pharmacological approaches