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Research has shown that ammoniums inhibitory effects on immune cells, such as T cells and macrophages, are closely associated with TME acidification

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doi: 10.3389/fpls.2020.575829 32 GhatakA.ChaturvediP.WeckwerthW

They are a rich source of soluble factors such as ROS, peptides, cytokines and enzymes that exert antimicrobial activities [257]