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Neurosurg Clin N Am

SAM is a methyl group donor for numerous methylation reactions in the brain, including those involved in the metabolism of neurotransmitters whose deficiency has been related to depression (102)

[1] [2] These effects may lead to decreased food intake and potentially impact overall nutritional status over time

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Prescriptions, particularly for controlled substances, may require an in-person evaluation depending on the state of residence and current federal regulations