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Notably, a recent study reported that mature oligodendrocytes display minimal detectable LDH expression and proposed that glycolytic products may be exported predominantly as pyruvate rather than lactate, with LDHA being more evident during development and remyelination (Spate et al., 2024)

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Unlike the DNA sitting safely inside the nucleus of your cellswhich is protected by a heavy armor of structural proteinsyour mtDNA is relatively exposed