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Nonetheless, administration of metabolic drugs as part of a regimen to reactivate the HIV reservoir may limit deleterious inflammatory consequences 182

Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis

HIV-1 factorsincluding Tat, gp120, Vpr, Nef, viral RNAs, and related miRNA, IncRNA and EVscollaboratively trigger pathogenic microglial responses, driving neuroinflammation and neurotoxicity in HAND through several converging pathways (Table 1)

Metformin, used as treatment for type 2 diabetes, induces B12 malabsorption and has also been associated with low total serum B12 concentrations (AlFawaeir & AlOdat, 2022)

Changes in expression levels of specific GSTs in response to certain xenobiotic compounds suggest substrate-specific roles of GSTs in xenobiotic detoxification [80,105,106]

Among them, GHK-Cu occupies a distinct position due to its copper-chelating properties and multifaceted biological activity