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Early diagnosis, stress management, and a personalized, multi-disciplinary treatment plan can help control inflammation, protect joint function, and prevent long-term complications

GSTs are classified into five distinct classes (alpha, mu, pi, sigma and theta) by their substrate specificity and primary structure

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doi: 10.3389/fphar.2025.1483548 Received 20 August 2024 Accepted 07 January 2025 Published 05 February 2025 Volume 16 - 2025 Edited by Luca Rastrelli, University of Salerno, Italy Reviewed by Ricardo Albuquerque, National University of Trujillo, Peru Minhajur Rahman, University of Chittagong, Bangladesh Tuoyi Wang, Qiqihar University, China Updates Copyright 2025 Anjum, Nasir, Naseer, Ibrahim, Rehman, Bashir and Tul Ain

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Paeonol is another important antioxidant and anti-inflammatory agent [179]