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Malaguarnera ( Tnf, Il6, Il1b ) and downregulates pro-fibrotic genes ( Acta2, Col1a2, Tgfb1, Pdgfrb, Pdgf-b, Pdgf-c ), reducing -smooth muscle actin (-SMA) and platelet-derived growth factor receptor beta (PDGFR) protein levels ( The anti-inflammatory and anti-fibrotic properties of L-carnitine underscore its potential to halt MASLD progression to advanced stages

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Mueed Z, Tandon P, Maurya SK, Deval R, Kamal MA, Poddar NK

44 Furthermore, alterations in brain omega 3/6 cardiolipin profiles found in the PPA rodent model could change inner mitochondrial membrane fluidity, and, thus, could potentially affect mitochondrial ETC complex interactions

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