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C3 is a downstream product of the metabolism of branched-chain amino-acids (leucine, isoleucine, valine) and of odd-chain fatty acids

Abramowicz WN, Galloway SD

( f-g ) H4K12ac or H3K23ac chromatin immunoprecipitation in U2OS-mCherry-LacI-Fok1 cells treated with the IDH1 inhibitor ( f ) or transduced with shRNA targeting TMLHE (shTMLHE) ( g ) alone or supplemented with KG or l-carnitine (l-carn) supplementation (n = 3 technical replicates representative from 2 independent experiments)

While the DRGs reside outside the cord, they are enclosed by TSPO-producing glial cells

It is the direct source the body uses to create Nitric Oxide

Stuttgart u.a.: Thieme