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Loss of function of the Parkin gene (PARK2) leads to impaired mitophagy (destruction of mitochondria by the cells homeostatic machinery) which produces a buildup of damaged mitochondria

Mehrotra M, Singh RR, Loghavi S, Duose DY, Barkoh BA, Behrens C, Patel KP, Routbort MJ, Kopetz S , Broaddus RR, Medeiros LJ, Wistuba II, Luthra R

A bacterial outer membrane vesicle-based click vaccine elicits potent immune response against Staphylococcus aureus in mice

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Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk Beta-thalassemia

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release