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however, the accumulation of polyubiquitination of uS10 in the absence of Ubp2 and Ubp3 seemed to inhibit the RQC activity (Fig

In the present study, we hypothesized that carnitine deficiency occurs in severely malnourished patients with eating disorders during refeeding and has adverse effects during the course of treatment, such as liver damage, hypoproteinemia, and poor weight gain

Notably, Nrf2 plays a dual protective role by both repressing neuroinflammatory signaling and promoting the transcription of antioxidant genes, establishing it as a compelling therapeutic target in neurodegenerative disorders [182, 183]

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It's about recognising which peptides affect haemostasis, through what mechanisms, and how those mechanisms overlap with anticoagulant pharmacology

Ethanol (EtOH) modulates CYP2A6 expression by activating the PKC/MEK/NRF2 pathway, potentially increasing HIV-1 replication in smokers