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3.2.1 Hirudin Hirudin is a primary active component derived from the medicinal leech ( Hirudo medicinalis Linnaeus, belonging to the Hirudinidae family), exhibiting anticoagulant, antifibrotic, antithrombotic, and anti-inflammatory properties, and demonstrating significant protective effects on the kidneys ( Initially, in the realm of metabolic regulation, research has demonstrated that hirudin can lower blood sugar levels and glycated hemoglobin in a rat model of DKD induced by a high-fat, high-sugar diet combined with streptozotocin (STZ)

doi: 10.1038/nature04648

Acute changes Neurological manifestations of mild TBI TBI is classified along a continuum with mild, moderate, and severe categories

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