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Second, research in animal models suggests that semaglutide activates GLP-1 receptors in the central nervous system, particularly in the brainstem area postrema and nucleus tractus solitarius, which are regions responsible for controlling nausea and vomiting responses

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10.1007/s00213-011-2495-x Psychopharmacology Summary Keywords dementia, Alzheimers disease, cannabis extract, cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), cannabis therapeutics, endocannabinod system Citation Coles M, Steiner-Lim GZ and Karl T (2022) Therapeutic properties of multi-cannabinoid treatment strategies for Alzheimers disease

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Am J Physiol Regul Integr Comp Physiol 292(1):R18-36