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Description
Because the redox states of these Cys thiols are regulated by the activity of thioredoxin (TRX) and GSH enzymatic systems and by the reductive power of NADPH (Fig

doi: 10.1196/annals.1297.047
However, there are conditions and risk factors that can compromise the endogenous production of glutathione by our liver and which are independent of our age

Statements Author contributions RS: Conceptualization, Investigation, Validation, Writing original draft, Writing review & editing

However, in the current era of -omics-based research, significant strides should be possible in terms of elucidating dysregulated enzymatic processes, as well as the roles of environmental factors such as pharmaceuticals

however, the substrates have been primarily restricted to cyclic ketones and activated cyclopropanes
