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doi: 10.1074/jbc.M110.172247 [DOI] [PMC free article] [PubMed] [Google Scholar] 322

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In recent years, the gut-brain-kidney axis has emerged as a compelling framework for understanding the interconnected pathophysiology of CKD

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Selenium deficiency leads to impaired TrxR activity, which disturbs cellular redox homeostasis and is closely associated with the pathogenesis of multiple disorders, such as cancer and inflammatory diseases (30,31)

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