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[PubMed] [Google Scholar] Konturek S
[DOI] [PMC free article] [PubMed] [Google Scholar] 355.Wang G., Li W., Chen Q., Jiang Y., Lu X., Zhao X
Plos one 17 , e0269486 (2022)
In the presence of HOCl, the first step involves the substitution of chlorine at the C3 position and the addition of water at the C2 position, resulting in the protonated 2-hydroxy-3-chloro intermediate
It is usually generated via a myeloperoxidase-catalysed reaction involving H + , chloride ion and H 2 O 2 by the activated neutrophils [28,29]
doi: 10.1111/jipb.12371
