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Thus far three clinical strategies to supplement GSH have been attempted including intravenous and oral administration or inhalation [92]

doi: 10.1073/pnas.111158898

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Although spontaneous remodeling occurs after ischemic stroke, these changes alone are insufficient to produce significant functional recovery [27]

Astrocytes respond by adjusting fuel (lactate) delivery, while microglia, guided by their metabolic checkpoint, monitor the interaction and decide to either support the synapse or prune it based on its metabolic health

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