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The STAT3 signaling pathway is closely associated with cell proliferation, differentiation, and apoptosis, and its dysregulation can lead to abnormal cell proliferation and malignant transformation (Pencik et al., 2023)
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doi: 10.1056/NEJMoa0909809
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The honest assessment is that AOD-9604 is a mild fat-loss enhancer, not a transformation agent
Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression
