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The intensive protocol (advanced users) For users with established tolerance, specific therapeutic goals requiring more aggressive treatment, or those addressing significant tissue damage, higher doses may be appropriate

2022 Sep 13;14(18):3767

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Cela ne dispense cependant pas de prudence : les patients souffrant dinsuffisance rnale, chez qui llimination est ralentie, doivent consulter un mdecin

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This is then converted to S-adenosylmethionine (SAM), the universal methyl donor
