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423 Specifically, the combination of psychological interventions and antidepressants effectively decreases the risk of relapse in cases of MDD

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Additionally, low methylation levels of the 5-HT2A gene were observed in the saliva of patients with schizophrenia and bipolar disorder, highlighting the potential of peripheral DNA methylation studies to identify novel biomarkers ( As previously discussed, DNA methylation changes in schizophrenia-related genes are integral to disease pathogenesis