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MOR activation is the most efficacious (Neumaier et al., 1988)
The alterations in melatonin synthesis are predictably essential in modulating the immune response with the locally-synthesized melatonin by immune-competent cells exerting anti-inflammatory actions at the site of infection (129)
Current therapies typically used in ASD do not directly address the underlying neuroinflammation
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Hathroubi S, Servetas SL, Windham I, Merrell DS, Ottemann KM
doi: 10.1016/j.yrtph.2006.06.007
