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This charge-switching mechanism, exemplified by PEG- b -poly(-lysine)-hydrazone- doxorubicin micelles from the cited study, enables targeted drug delivery with improved intracellular release and reduced systemic toxicity, highlighting the therapeutic advantage of pH-sensitive hydrazone bonds in nanocarrier design [46]

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Physella acuta snails were estimated to be juveniles and adults based on their shell lengths (Nez, 2010) ranging from 3.94 mm to 8.47 mm, with a mean of 6.68 mm (SD 1.045 mm)

The authors of another article report that low levels of mycotoxins cause oxidative stress and may be one of the major causes of mitochondrial dysfunction
