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218 Another study that analyzed data from 10,480 NHANES (20052016) participants found those with the highest folate combined with the lowest B 2 intake had the highest rate of death from cardiovascular disease during an average of 8.5 years of monitoring

In this context, a newly published systematic review including seven clinical trials showed that the application of vitamin B12 supplementation for metformin-treated T2DM patients will be valuable in preventing or treating vitamin B12 deficiency and neuropathy and should be considered during the T2DM management plan[32]

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Shingles is an infection caused by the same virus that causes chickenpox: the varicella-zoster virus