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HCK expression is significantly upregulated upon activation of the NLRP12-PANoptosome in response to infection or homeostatic disruption, suggesting its potential as a therapeutic target for inflammation and pathology mitigation (Nadendla et al., 2025)

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Under normal physiological conditions, ROS play an essential role in cellular homeostasis by maintaining biological functions (Jaboska-Trypu et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Akinyemi F.T., Adewole D.I